2,082 search results for “binding study advies bsa” in the Public website
-
Maria RiepFaculty of Archaeology
-
Jelle BruningFaculty of Humanities
-
Kinetics for Drug Discovery: a Case for the Adenosine A3 receptor
Supervisor: Lizi Xia
-
Kinetic profiling of positive allosteric modulators of the mGlu2 receptor
Supervisor: Maarten Doornbos
-
Yujing TanFaculty of Humanities
-
Guita WinkelFaculty of Humanities
-
Erik-jan ZurcherFaculty of Humanities
-
Kiyan ForoutanFaculty of Humanities
-
Hélène NutFaculty of Humanities
-
Daný van DamFaculty of Humanities
-
Bastian Still -
Mahmood YenkimalekiFaculty of Humanities
-
Supercritical carbon dioxide spray drying for the production of stable dried protein formulations
Promotor: W. Jiskoot, Co-promotor: H.A. Every
-
Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
-
From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
-
Author, Reader, Book: Medieval Authorship in Theory and Practice
This collection brings into conversation several kinds of scholarship on medieval authorship which have tended to remain separate over the last two to three decades, a period of steadily increasing scholarly interest in this topic.
-
Leiden Jewish Studies Network awards second 'Best Thesis in Jewish Studies'
This November, Leiden Jewish Studies Network has presented the Best Thesis in Jewish Studies award to a highly talented Leiden graduate, Lotte-Sofie Groenendijk, and awarded an honorable mention to Nasreen Javanjoo. The two theses stood out with their insightfulness and academic rigor among others written…
-
Michael HerzfeldSocial & Behavioural Sciences
-
Shuqi JiaFaculty of Humanities
-
Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates
We have examined sequences from the ligand-binding domain of the nicotinic acetyl choline receptor (nAChR) in 148 vertebrate species. We are in interested in this receptor because the α-neurotoxins of many venomous snakes binds to this receptor in its location at the neuromuscular junction in all ve…
-
Intracellular allosteric modulators for human CC chemokine receptors
Supervisor: Natalia Ortiz Zacarías
-
Nathal DessingFaculty of Humanities
-
Programme structure
Studying International Relations and Organisations (IRO) you will address transboundary issues from a social sciences point of view. It is an international 3-year programme with a strong focus on current global affairs.
-
Allosterism
The recognition that there may be more, so-called allosteric binding sites on a given receptor has also fueled our synthetic efforts. Over the last few years we have focused on many drug targets (adenosine A1, A2A and A3 receptors, the mGlu2 receptor and a classic ‘anti-target’, the hERG channel) to…
-
Computational Drug Discovery
Research in this group, headed by Gerard van Westen, focusses on computational methods integrated in different parts of the drug discovery process. More specifically, topics include innovative treatments for cancer, selectivity modeling, translational research, allosteric modulation, drug resistance…
-
Ali ShobeiriFaculty of Humanities
-
The synthesis of mannose-derived bioconjugates and enzyme inhibitors
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee
-
Enzyme-substrate interactions in the processive enzyme xylanase
The primary goal of this research is to deepen our understanding of substrate-enzyme interactions in Glycoside hydrolases. For this purpose, Bacillus circulans xylanase (BcX) has been selected as a well-established model to examine the Michaelis complex and glycosyl-enzyme adduct.
-
Total Synthesis of Alginate and Zwitterionic Sp1 Oligosaccharides
The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.
-
Cannabinoid receptor 2 as a ‘drugable’ target: kinetic profile of novel receptor ligands
Supervisor: Andrea Martella
-
Edmund AmannFaculty of Humanities
-
Ugur DerinFaculty of Humanities
-
Onur AdaFaculty of Humanities
-
Focus on kinetics for better drug development
Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…
-
Weishuo LiFaculty of Archaeology
-
Shahab DaneshvarFaculty of Humanities
-
Mubarika NugraheniFaculty of Humanities
-
Jonathan StöklFaculty of Humanities
-
Deniz TatFaculty of Humanities
-
David HenleyFaculty of Humanities
-
James McAllisterFaculty of Humanities
-
‘Take medicine target saturation into account’
Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…
-
Olga van MarionFaculty of Humanities
-
Berthe JansenFaculty of Humanities
-
Eric JorinkFaculty of Humanities
-
Career prospects
A master in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.
-
About
Learn about the Institute’s mission, structure and academic community within Leiden University’s Faculty of Humanities.
-
Ajay GandhiFaculty of Governance and Global Affairs
-
Molecular Pharmacology
In this research group, headed by Laura Heitman, novel receptor concepts in drug discovery are studied, aiming to increase the effectivity of medicines. Many drugs act via so-called G protein-coupled receptors (GPCRs) and therefore our research is mainly focused on understanding and improving drug-receptor…
-
Covalent inhibitors of G protein-coupled receptors: the case of adenosine receptors
Supervisor: Xue Yang