A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

At the end of the year we always compile a list of our most interesting, most popular articles from that year. In the crazy year that was 2020 one topic was at the forefront of everyone’s minds: coronavirus. Fortunately, there was also room for other stories.

Plants love favourable microbes such as bacteria and fungi: they grow better and become healthier. Jos Raaijmakers, Professor of Microbial Ecology, is in search of the right microbes to be used in agriculture. Inaugural lecture 13 November.

Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…

Bacteria and fungi on organic dairy farms are significantly different from those on conventional farms. That was discovered by postdoc researcher Sofia Gomes and her supervisors Nadia Soudzilovskaia and Peter van Bodegom in collaboration with the Louis Bolk Institute and Naturalis Biodiversity Centre.…

Using E. coli bacteria to convert a toxic compound in the soil on Mars into oxygen to make life on the planet possible. A team of thirteen Leiden students are taking part in the annual iGEM competition with an entry based on this idea. iGEM is an international competition for students where they use…

At the start of the COVID-19 pandemic, researchers from 15 departments at Leiden University Medical Center (LUMC) realised they could do more for patients if they joined forces. This is how the BEAT-COVID group has been able to rapidly gain knowledge about COVID-19, the role of the immune system and…

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.

Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.

Majid Khan, born and raised in Pakistan, left his wife and daughter behind to do research in Leiden. After obtaining his PhD, the Netherlands has taken a special place in his heart. ‘Biking in the rain and wind was weird. But I loved it.’

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

Three Leiden researchers will each receive a Vici grant of 1.5m euros. They are historian Cátia Antunes, cell biologist Dennis Claessen and archaeologist Marie Soressi. This grant from the Dutch Research Council (NWO) will give them the opportunity to form their own research group over the next five…

Within a month, the Wake Up to Corona crowdfunding campaign had already raised 600,000 euros for corona research in Leiden. The goal is to raise enough money for the LUMC to set up a second laboratory that is safe enough for research into the new virus. The initiative has not escaped the attention of…

Are Weyl particles the ideal conductors? Do cells without a cell wall play a role in chronic Tuberculosis infections? Carlo Beenakker and Dennis Claessen want to answer these questions. They both received a KLEIN grant from the NWO. With these grants, NWO wants to stimulate innovative, fundamental r…

Inaugural lecture

Valedictory lecture

An overview of awards and prizes granted to our staff and students in 2020, as well as special appointments at Leiden University and other institutions.

What happens to the different waste streams?

The Janssen-Cilag International N.V COVID-19 vaccine has received authorization for emergency use by the European Medicines Agency (EMA) on March 11. The vaccine was developed with fundamental support from the Molecular Virology group of the Leiden University Medical Centre (LUMC).

Come to the Night of Discoveries art and science festival on 16 September. Various researchers from the university are speaking at the festival.

At the New Year’s reception of the Faculty of Science on 6 January, it was announced that Annelien Zweemer, Leiden Academic Centre for Drug Research, has been awarded the ‘Discoverer of the Year 2014’ prize. Matteo Brogi, Leiden Observatory, wrote the best dissertation in 2014 and Dennis Claessen, Institute…

Imagine that you need to travel, but you don’t have a car and you’re dead broke. What do you do? Hitchhiking, of course! Leiden biologists found that certain bacteria use this very same tactic: their spores hop on motile bacteria and use them as a taxi, ensuring they reach the right environment to f…

Tackling key challenges of Chemical Biology and Medicinal Chemistry to aid drug discovery is one of the focus areas of Leiden University. To this end, the Leiden Early Drug Discovery & Development network (LED3) was established by the Leiden Institute of Chemistry (LIC), the Institute of Biology Leiden…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

After four years of hard work, the time has finally come: your thesis is finished. But who of your family and friends will ever read it? Biologist Lizah van der Aart decided to make a magazine for layman. 'It was precisely the explanation of the difficult, fundamental parts that gave me good tools for…

From 1 October onwards, Dennis Claessen and Marcel Schaaf will be the new directors of education of Biology. They will replace Han de Winde. Schaaf will be responsible for the bachelor, while Claessen will mainly focus on the master tracks of Biology. We gave students and the education office the change…

Turning beer waste into a useful, sustainable product. That was the mission of students from Leiden at the international BISC-E event. The biology students challenged themselves and won third place in the Dutch finals of this competition. For this, they used the simple formula: Grain + fungus = coas…

A team of students from Leiden and Groningen took the second prize at the European final of the BISC-E sustainability competition. Last June, the team had already won the Dutch finals. The students came up with ‘Suckerspheres’, a natural alternative to the plastic micro-particles that are still frequently…

Two years ago, Amanda Henry joined the Faculty of Archaeology’s Archaeological Sciences department. She investigates diet and human evolution, with a specific focus on plant foods. ‘Most of the studies on the prehistoric diet focus on meat and hunting. This just didn’t make sense to me.’

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

A new AI model will soon be able to predict the risk of infection in postoperative patients. This will allow healthcare providers to take preventive measures and detect complications at an earlier stage.

The Institute of Biology Leiden has a new visiting professor as of the first of May. Bioinformatician Marnix Medema holds the Van der Klaauw chair for a year and looks forward to scientific collaborations and to boost the bioinformatics education.

As of 1 May 2018, Nicole de Voogd has been appointed as Professor by special appointment Global change and marine ecosystems at the Institute of Environmental Sciences (CML). She is currently senior researcher at Naturalis Biodiversity Center in the field of tropical marine ecosystems.

All acute care staff at Leiden University Medical Center have received their first and sometimes even their second dose of the coronavirus vaccine. But how long will you be protected after vaccination and what does the genetic material of the virus do in the vaccine? Our virologists Ann Vossen and Leo…

The adventure of iGEM Leiden has come to an end. The result: prizes for Best Therapeutic Project and Best Model, a gold medal, a successful crowdfunding campaign and of course their open-source research findings, which are available for the scientific community.

Eleven ambitious Leiden students hope to heal burns with a special substance from squid teeth. They are taking part in the international iGEM competition. They need to raise almost 10,000 euros to fund their project this summer.

When a bacterium becomes resistant to one antibiotic, it may sometimes become more sensitive to another. This biological side-effect offers an unexpected opportunity in the fight against antibiotic resistance.

Preventing viral infections from being transmitted through blood transfusion and organ transplantation lies at the heart of the work of medical microbiologist and virologist Mariet Feltkamp and her team.

Lecture

10 October is the Day of Sustainability. What is the current status of sustainability at Leiden University? Things are moving ahead. Professor of Environmental Biology and Dean of the Faculty of Science, Geert de Snoo, outlines a new prospect: biodiversity.

World-famous among astronomers, humble, and averse to conventions. On 23 April, the Dutch biography about Henk van de Hulst was published. Biographer Dirk van Delft: ‘This remarkable man deserved a biography.’

Yeast, alpacas, and antibodies. They may seem unrelated, but within the project of the Leiden iGEM students, they come together perfectly. For the international synthetic biology competition iGEM, the team is working on an innovative method to produce nanobodies—a special form of antibodies—using brewer’s…

The genetic code of the new coronavirus has been found: it is closely related to the SARS virus from 2003. Professor of Molecular Virology, Eric Snijder, has been researching coronaviruses for years. We asked him a few questions about the outbreak. ‘It’s still unclear whether this new virus is more…

Lecture, Studium Generale

Lecture

Over the past year, many of our staff and students have won prizes, been awarded a substantial grant or been appointed to an academic association or a position in public life. All of these are good reasons to include them in our 2019 Hall of Fame. We are proud of them all.