Doctors should work with patients with bone and soft-tissue tumours to find the best personal treatment strategy says Prof. Michiel den de Sande. He has developed an app that helps choose the right treatment. Van de Sande was appointed Professor of Orthopaedics with a particular focus on paediatric…

Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

Find out how to apply for Transfusion Medicine and Cellular and Tissue Therapies.

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

Study information

Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

More and more medicines are becoming available that target a tumour’s specific traits. The use of chemotherapy is continually undergoing improvement.

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.

Strengthening a cancer patient's own immune system so that the body itself can better destroy cancer cells. This is at the heart of immunotherapy, the most promising progress in cancer treatment in recent years. In order to drive this development further, the Netherlands Cancer Institute-Antoni van…

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

In the research programme Drug Discovery & Safety, we are interested in the efficacy and safety of new drugs and novel means to decipher these aspects. Hence, we employ advanced imaging and high-throughput screening techniques next to computational approaches such as chem- and bioinformatics.

How effective is eye movement desensitization and reprocessing therapy in targeting epilepsy-related anxiety?

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

This Master enables you to practice professional activities such as: lead research projects and develop technically qualified projects in the field of transfusion medicine.

A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

In order to optimize treatment, it is necessary to closely monitor and manage the patient’s health status by means of ‘precision diagnostics, personalized prognosis and targeted therapy’. The specialisation combines the techniques and applications of these sensing (monitoring) and stimulation techniques.…

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

An overview of Quantitative Pharmacology projects

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…

Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Our team is involved in the translation and adaptation of several questionnaires, for research purposes. Information about each questionnaire is listed below.

As a psychologist and pilot, Bert Busscher is interested in the phenomenon often termed as fear of flying. Busscher discovered that the heart rate of a person undergoing a therapeutic flight shows how much they still suffer from fear of flying. The post-flight heart rate can even predict whether the…

Op zaterdag 27 februari organiseert Stichting Zenobia het Vijftiende Zenobiacongres, met de titel Van de Levant tot de Lagune: Venetië en het Oosten. Het congres zal online plaatsvinden en is vrij toegankelijk.

Registration for the Co-Align 2023 conference is open!

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

Are you looking for a research project?

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?

Het project heeft plaats gevonden onder begeleiding van Prof.dr.ir.Tjerk Oosterkamp. De titel van de presentatie is:

Op vrijdag 4 april 2025 organiseert de werkgroep Stedengeschiedenis een bijeenkomst bij de Rijksdienst voor het Cultureel Erfgoed onder de titel ‘Archeologie en de stad’. De studiedag is gratis en voor iedereen toegankelijk.

Het project heeft plaats gevonden in de Gorter LUMC groep onder begeleiding van Dr. J.W.M. Beenakker en prof.dr.ir. T.H. Oosterkamp . De titel van de presentatie is:

Het project heeft plaats gevonden in de KM3NeT Nikhef Amsterdam groep onder begeleiding van Dr. D.F.E. Samtleben en Prof.dr.ir. T.H. Oosterkamp. De titel van de presentatie is:

Het project heeft plaats gevonden in de QMO groep onder begeleiding van Dr. Michiel de Dood en Dr.ir. Sense Jan van der Molen. De titel van de presentatie is:

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck