The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

When combined and used by specific people located in time and place, words can express something more than, different from, or even the opposite of their dictionary meanings.

Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

This thesis describes a study from both a theoreticaL and an experimental point of view.

On the 4th of June, Saskia Lensink successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Saskia Lensink on this achievement!

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

The project investigates how bilingual speakers navigate lexico-syntactic features, including grammatical gender, classifier systems, and the linear order of adjectives and nouns, across Spanish and Chinese in both unilingual and bilingual contexts.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Shared, general-purpose labs.

Leiden Journal of Pottery Studies 21, 2005

Promotor: Prof.dr. C.W.J. Beenakker

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterize and predict variation in treatment response and enhance translational drug development strategies.

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Exploring Late Bronze Age attitudes towards martiality through experimentation and micro-wear analysis

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

On the 16th of December, Ruixue Wu successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Ruixue on this achievement!

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

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Leiden archaeologists have set fire to a reconstructed Neolithic house in Horsterwold: all in the name of science. Studying the remains will help them understand present and future finds.

Promotor: Prof.dr.ir. J.W.M. Hilgenkamp, Prof.dr. J. van den Brink

Studying Physics is an exciting journey through the foundations of nature: from the infinitesimal (particle physics) to the grandest scale (cosmology). Physics is a varied study programme that provides a solid foundation in theory and experimentation, with attention devoted to their practical applic…

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Explore "Analysis of Repeated Measurements" at Boerhaave Nascholing. Learn statistical methods for correlated data in time. Read more here.

Explore "Analysis of Repeated Measurements" at Boerhaave Nascholing. Learn statistical methods for correlated data in time. Read more here.

Physicists in Leiden have built a microscope that can measure no fewer than four key properties of a material in a single scan, all with nanoscale precision. The instrument can even examine complete quantum chips, accelerating research and innovation in the field of quantum materials.

Without electronics carrying out computational tasks our daily lives would look very different. Devices such as elevators, vending machines, turnstiles, washing machines and even traffic lights use a simple form of electronic computing to switch from state to state. But, what if power supply is not…

Sense Jan van der Molen is vanaf 1 maart de nieuwe wetenschappelijk directeur van het Leiden Instituut voor Onderzoek in de Natuurkunde.

Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

What did our distant ancestors eat and how did they prepare their food? For the length of a month, experimental archaeologist Diederik Pomstra subjects himself to a rigorous palaeodiet. He is vlogging about his experiences to reach a non-academic audience.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Source: PLoS ONE, Volume 10, Issue 3 (2015)

What role play stress and fear in forming of nocebo hyperalgesia?

To what extent can literary strategies deepen and enhance research in and through the visual and performing arts, as well as for research in academia?

Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.

This project looks at how the native language influences processing mechanisms of non-native language(s) as well has how it influences brain structure and functional connectivity.

Master projects are available in

This thesis investigates the connection between tonal realization and tone change (tone sandhi) in Wenzhou Chinese, and whether and how such a connection is conditioned by prosodic structure and focus marking.

Leiden has a strong tradition in theoretical physics, thoroughly linked with experimental disciplines.

Sound & Score brings together music expertise from prominent international researchers and performers exploring the intimate relations between sound, score and notation, and the artistic possibilities that this relationship yields for performers, composers and listeners.

The Leiden Institute of Physics (LION) offers bachelor and master level education in physics at Leiden University.