The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

This focus area adresses the mental well-being of people of all ages, from infants to the elderly. The emphasis lies on understanding, preventing, and treating mental health problems in a variety of contexts, such as the family, school, and work environment. We carry leading research and education programmes…

Kohei Suzuki and his co-authors reflect on their extensive scholarly experience teaching comparative public administration across diverse countries including Canada, the Netherlands, Qatar, and the United States.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Complaints against decisions not to prosecute in socially sensitive issues.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

What is the neural basis of social decision-making across childhood, adolescence and adulthood and what are the developmental patterns in terms of behavior and brain activation?

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

In their vision trajectory, the Office for the Senior Civil Service (in Dutch: Bureau Algemene Bestuursdienst) communicated its plan to renew its vision on public leadership. Over the course of 2021, the Leiden Leadership Centre contributed as a scientific partner to the substantiation of this visio…

Our core themes, which our programmes are about, are: Public Affairs, Leadership, Political-Administrative Sensitivity, Safety and major social issues.

This dissertation concerns the role of analogy in Kant’s “Critique of the Teleological Power of Judgment”, especially the role of analogy for the formation of the concept of a natural end (Naturzweck). A ‘natural end’ is a ‘regulative concept’ of the reflective power of judgment, that is, a heuristic…

This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.

This project aims at studying the social media reception of African publications as covered by the most important “altmetric” sources.

An extra-long procession with musical accompaniment will mark the beginning of the university’s 450th birthday celebrations on 7 February.

This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…

How to reconstruct the middle parts (videlicet haute-contres, tailles and quintes) from French orchestral pieces, which survived only in their reduced forms (featuring primarely dessus and continuo), according to historical examples?

In this dissertation the author digs into the constituent elements of River Plate tango in order to decode how specific musical materials were organized and combined by four outstanding musicians: Pugliese, Salgán, Piazzolla and Beytelmann.

The Focal Area Engagement & Inclusion at CWTS aims to create a more diverse, inclusive and engaging science ecosystem.

As a PhD, there are many ways to participate in the academic life of the Institute and the University. We strongly encourage you to do this, as it will greatly enrich your PhD period. LUCAS has a vibrant PhD community, which organizes several initiatives. All PhDs are warmly invited to join, either…

Investigating domestic crafts and subsistence activities through experiments and material analysis

Responsible Research and Innovation (RRI) implies that societal actors (researchers, citizens, policy makers, business, third sector organisations, etc.) work together during the whole research and innovation process in order to better align both the process and its outcomes with the values, needs and…

The RISIS project aims at creating a distributed research infrastructure to support and advance science and innovation studies. This will give the field a strong scientific push forward, and at the same time, provide a radically improved evidence base for research and innovation policies, for research…

Security and Legitimacy is one of the three organisational clusters of the Institute of Political Science.

Het Empower your PhD-project is een universiteitsbreed project, geïnitieerd vanuit de Faculteit der Sociale Wetenschappen (FSW)

U-Multirank is an alternative approach to international ranking of higher education institutions (HEIs) worldwide. This analytical tool is user-driven and multi-dimensional by design. The current version (2016/2017) includes 1 600 HEIs. The ranking system compares the relative performance of HEIs (mostly…

Who is funding African science? How are different African and international funders interacting and contributing to develop scientific research in the continent? Are there potential inadvertent synergies among research funders that can be identified? These and similar questions are at the heart of this…

This project is opening up the possibility of systematically studying research teams from a broad perspective, by developing specific bibliometric methodologies able to identify active collaborative research teams in Africa. Based on the extensive experience of CWTS and CREST, this project represents…

This team ensures that all Una Europa activities at Leiden University and LUMC run smoothly, and provides support to colleagues directly involved in Una Europa initiatives.

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Promotor: E. Bouwman, Co-promotor: S. Bonnet

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

Marius Staring, Associate Professor at the LUMC has been awarded the Chan Zuckerberg Initiative funding for further development of image processing software Elastix

As of 1 February 2009, PhD applications should no longer be sent to the International Office to be processed. The Graduate School will deal with its own applicants in future.

This project, commissioned by DG Research and Innovation, aims to provide information for policies that lead to the creation and improvement of the conditions which will allow researchers and European industries to safely master the properties of nanomaterials and to innovate with nanotechnology.

The aim of this study is to further develop the Open Science Monitor, which started as a pilot study.

PathOS aims to contribute to a better understanding and measurement of Open Science impacts and their causal mechanisms. This is pivotal in order to develop effective OS policy in the EU (European Union). It will do so by collecting concrete evidence of OS effects, by studying the pathways of OS practices,…

In this consortium CWTS (Leiden University) collaborates with two Swedish SMEs: Monocl AB and Recorded Future AB. Monocl AB delivers intuitive analysis software to Life Sciences professionals in support of strategic decisions and improvement of business performance. Recorded Future AB is an organization…

Comparative and Dutch Politics is one of the three organisational clusters of the Institute of Political Science.

Computer scientist Bas van Stein conducted research at Tata Steel and BMW on how their production processes could be streamlined and optimised on the basis of data. As part of his research he developed some innovative products. PhD defence 20 September.

This dissertation approaches collections of Andean mummies in European national and university museums as the focus to understand the relationship between objects, documents, and the practice of collecting in the period from 1850 to 1930. Over 200 mummies, kept by 18 different museums in Western European…

At the Young Academy Leiden, we are closely engaged with the everyday practice of scientific research and education. From this perspective, we also contribute to the wider conversation on policy. In our policy work, we aim to be an independent and constructive voice, sensitive to current developments,…

Modern society is connected through electronic and mobile devices, which we call the Internet of Things (IoT).

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Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

Promotor: P.M. Brakefield

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.