The aim of the research programme Systems Pharmacology lies in the development of personalised medicine strategies, and development of new systems-based approaches in translational and clinical pharmacology.

The programme group Clinical Neurodevelopmental Sciences is one of the six groups within the Institute of Child and Education Studies at Leiden University. The group participates in all stages of the education programme: the bachelor's, master's and research master's programme.  The group is particularly…

Brave Little Ones is a research group that investigates the potential prevention of anxiety disorders in children aged 3-6 years old who are very shy or anxious.

This focus area adresses the mental well-being of people of all ages, from infants to the elderly. The emphasis lies on understanding, preventing, and treating mental health problems in a variety of contexts, such as the family, school, and work environment. We carry leading research and education programmes…

These awards honour researchers who turn scientific insight into real-world impact. From master’s students to postdocs, they highlight exceptional work in life sciences, health sciences, biotech, or environmental health sciences with data science at the core. Meet the 2025 winners.

On this page you will find more information about the selected projects of the Justice, Equity, Diversity and Inclusion (JEDI) Fund for 2022.

Lecture

Met groot plezier heeft de Universiteit Leiden van 1 tot 4 november het X Congreso Internacional de la Asociación de Hispanistas del Benelux (AHBx) georganiseerd, met het thema Transhispanismos: contactos y contagios (Transhispanismes: contact en besmetting). De AHBx is een platform in de Benelux dat…

Ward Hoskens started ten years ago as an intern at one of Leiden's most iconic buildings: the Pieterskerk. Now he is doing his PhD on the question of how the function of this 'church that is no longer a church' changed over recent centuries.

Book by Soledad Valdivia Rivera

Promotor: Prof.dr. H.L.V. Linnartz

Contact Bio-organic Synthesis

Appropriate animal models for intradermal vaccine delivery are scarce. Given the high similarity of their skin anatomy to that of humans, minipigs may be a suitable model for dermal vaccine delivery.

Professor at the School of pharmaceutical sciences, University of Geneva - Switzerland

Historical geo data are gaining in importance. Provided that they are exactly geo referenced, they can be stored into a GIS and thus be combined with all kinds of maps (topographical, pedological, etc.) and datasets. This makes it possible to analyze historical developments in space and time on a detailed…

General

Waarom is empirisch-juridisch onderzoek van belang voor de rechtspraktijk en het wetenschappelijke onderzoek? Op die vraag kregen masterstudenten van de afstudeerrichtingen civiel recht, ondernemingsrecht en financieel recht antwoord tijdens het congres over empirisch-juridisch onderzoek en het privaatrecht…

This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.

The healthcare system still treats children as though they are small adults. And that approach does not work, says Lissy de Ridder, professor and head of Paediatrics, in her inaugural lecture.

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Mensen worden steeds ouder. Soms in goede gezondheid, soms zijn er uitdagingen die de kop op steken. Met onderzoek, innovatief onderwijs en co-creatie met oudere mensen werken studenten van de master Health, Ageing and Society aan oplossingen voor deze uitdagingen.

Vaccines are an extraordinary category of biopharmaceuticals. They are usually prophylactic and come in many types, from whole bacteria to peptides and nucleic acids. They are very cost effective and almost every human on the planet is vaccinated. The latter mandates that vaccines have to be extremely…

Cecily Rose, Assistant Professor at the Grotius Centre for International Legal Studies, has been involved in informing media reports about the recent provisional measures order delivered by the International Court of Justice (ICJ) in The Gambia v Myanmar case.

There is much unrest among local stallholders in Utrecht. Owners who for decades had a permanent pitch for their stall are no longer guaranteed this due to new European regulations. So no more benefits for the current stallholders which is causing them great uncertainty and frustration.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?

An important hormone excreting gland in the human body is the pituitary

In order to optimize treatment, it is necessary to closely monitor and manage the patient’s health status by means of ‘precision diagnostics, personalized prognosis and targeted therapy’. The specialisation combines the techniques and applications of these sensing (monitoring) and stimulation techniques.…

Our mission is to advance the understanding of mental health of individuals with a history of stress and/or trauma through rigorous interdisciplinary research, integrating insights from clinical psychology, neurobiology, and social sciences. We are committed to translating our findings into innovative…

The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics.

The aim of this study is to identify the side effects during treatment with methylphenidate and to investigate how children experience the use of the medication (such as Ritalin, Concerta and Medikinet).

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Welcome to the website of the ‘Brave Little Ones’ research group!

Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…

The NVIC has published a series of scholarly publications in Arabic and several European languages.

PhD defence

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

Here you will find articles written by and about the Brave Little Ones research group.

Jasmina Mačkić, assistant professor at the Europa Institute, delivered a lecture about topics related to discrimination during the Equal Rights Conference ‘Show Your True Colours’ in Leiden. The conference was organised by AEGEE-Leiden from the 24th up to an including the 27th of May 2018.

Lecture, Research Seminar

Aquí pueden encontrar el programa del congreso.

(1) What are the institutional factors that influence AI adoption and implementation? and (2) How does AI reshape the exercise of administrative discretion within public organisations, and how do adoption and implementation choices moderate these effects?

Overview of Leiden publications on Central Asia. For additional publications dedicated to a single country, please go to individual pages of the researchers, which you can access through the Researchers page.

Here you will find an overview of the Spaces for Active Teaching and Learning already implemented at Leiden University and LUMC. These rooms vary in size, location, material affordances, and technological affordances, and thus vary in the forms of pedagogy they best support. You can use this site as…

Access to information is a human right (United Nations, 1948). Information technology, such as search engines and recommender systems, has become the key mediator and facilitator to connect people to information (White, 2016). Conversational artificial intelligence (AI) technology is increasingly being…