1,480 search results for “patient involvement” in the Public website
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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Tanzania
This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Medicine with Kilimanjaro Christian Medical Center in Tanzania.
- Lectures
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Aging and Immunity
The Aging and Immunity group is led by Dr. Amanda Foks. In this group we aim to investigate how aged immune cells contribute to atherosclerosis and identify novel therapeutic targets and strategies to extend health span and inhibit cardiovascular disease.
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Brain networks and the initial stages of dementia
Dementia is a progressive disease, diagnosed at a relatively late stage when intervention may not be effective. Aim of the research is to study scans of brain networks to help discover the early network changes related to dementia. Early diagnosis may benefit effectiveness of future treatment.
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Chronobiology of depression
What are the circadian disturbances underlying depression vulnerability? How are they related to mood, cognition and sleep ?
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Systems pharmacology of human neuroendocrine disease entities
An important hormone excreting gland in the human body is the pituitary
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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Student projects
Are you looking for a research project? We have projects available for motivated 6–9-month internship students with particular interest in organic/polymer synthesis, formulation development, gene delivery, protein delivery, and the preliminairy in vitro screening of drug delivery platforms. Students…
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Cardiovascular Pharmacology
The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.
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Career prospects
With an MSc degree in Physics and Science Communication & Society you are well prepared for a broad array of career prospects in research or industry. The master’s degree is an excellent preparation for a career at the interface of science and public affairs.
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Research
The University wants its teaching and research to have the maximum academic, cultural, social and economic impact.
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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The recognition process of youth with problematic anxiety in general practice
Do general practitioners recognize children with or at risk of problematic anxiety and is there a pattern that might help differentiate those with and without anxiety disorders in general practice?
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Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Single Cell
The single cell group (SCG) is part of the Metabolomics & Analytics Centre Our research is centered around developing innovating analytical methods tailored for small-volume, or single cell analysis to enable metabolomics-driven systems biology in personalized health strategies. We are always on…
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Topic: Stress and stress-related disorders
The precise psychobiological mechanisms leading to chronic physiological stress responses have not been sufficiently explained, although stress is a major risk factor for disease and early death. A problem for conventional stress theory is that most of these responses seem to occur in situations without…
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Exploratory Data Mining in Multimodal data
The change from a closed institution to an open living environment for patients with late stages of dementia will give the patients more freedom in their day-to-day life. The effect of this change on the patients’ mobility, activity and interaction with others will be assessed with sensor technology…
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Shy parent, shy child?
Delineating psychophysiological endophenotypes of social anxiety disorder
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics.
- Practical Information
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Career prospects
After graduation you have a lot of opportunities: the field of science communication is very broad. You can also aim for a career in industry or research.
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Exploring the life of amulets in Palestine
On the 1st of December Marcela A. Garcia Probert successfully defended a doctoral thesis and graduated.
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Overview
The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Career prospects
After graduation you have a lot of opportunities: the field of science communication is very broad. You can also aim for a career in industry or research.
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Interested in healthcare and wellbeing?
Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…
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Interested in healthcare and wellbeing?
Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to healthcare innovation, from lifestyle to healthcare policy: you’ll learn to understand societal…
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Portal for prospective Indonesian Students
The portal for prospective Indonesian Students contains information about the possibilities to study at Leiden University in the Netherlands.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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Globalizing Palliative Care? A Multi-sited Ethnographic Study
This project investigates the globalization and cultural mediation of palliative care practices, policies and discourses.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Drug discovery and development
New or improved treatments for chronic and acute illness.
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Medicine Students
Are you currently studying medicine and considering the master's Health, Ageing and Society? Read more about what the master's programme can mean for you!
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Interested in healthcare and wellbeing?
Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to sustainable cities, from lifestyle to healthcare policy: you’ll learn to understand societal…
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Interested in healthcare and wellbeing?
Are you curious about how health, behaviour and our living environment are connected? At Leiden University, you’ll explore how people grow up, age and live together in a changing world. From mental health to sustainable cities, from lifestyle to healthcare policy: you’ll learn to understand societal…
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Dutch fertility clinic faces legal consequences over false information
The largest fertility clinic in the Netherlands lied to women, sperm donors, and the Health and Youth Care Inspectorate. On ‘Nieuwsuur’, Mirjam Sombroek van Doorm, Professor of Law and Health, foresees legal consequences: 'The situation is too serious.'
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Anne Krause-Utz
Faculty of Social and Behavioural Sciences
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Matching medication to DNA leads to 30% fewer side effects
According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.
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Vidi grant for The Future of Dying
The Future of Dying: End-of-Life Care in a Time of De-medicalized Death explores how patients, their relatives, and healthcare providers make decisions about end-of-life care when such treatments are readily available.
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Exploring the materials and heritage involved in the Belt and Road Initiative
Dr Maikel Kuijpers, a staff member at the Faculty of Archaeology and a guest researcher at the Centre for Environmental Sciences (CML), is participating in an exploratory interdisciplinary study on the Chinese Belt and Road Initiative (BRI). Made possible by a Seed Fund of the Leiden University Global…
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Helen Pluut involved in interdisciplinary initiative that is awarded a Kiem grant
Leiden University has made available Kiem (seed) grants of €10,000 - an initiative for developing new interdisciplinary, interfaculty research partnerships and encounters. Helen Pluut is part of a Kiem team, one that brings together researchers from Leiden Law School, LUMC, FSW and ICLON (and Young…
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Government unaware of Dutch involvement in Iran nuclear weapons programme sabotage
In 2007, a spy from the Dutch General Intelligence and Security Service (AIVD) planted a destructive computer virus at an Iranian nuclear site, halting the Iranian nuclear weapons programme. Dutch newspaper ‘de Volkskrant’ has revealed that the AIVD kept the crucial role of the Dutch spy a secret from…
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Dietsje JollesFaculty of Social and Behavioural Sciences
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Paul VedderFaculty of Social and Behavioural Sciences