3,133 zoekresultaten voor “as a modernities and traditions” in de Publieke website
-
Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
-
The Diving Dutchman: het marien-gravimetrisch onderzoek van F.A. Vening Meinesz (1887-1966)
Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra
-
A chemical biology approach to explore lipid metabolism in neurological disorders
Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.
-
Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.
-
Prediction of spatial-temporal brain drug distribution with a novel mathematical model
A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.
-
Selectieroutes (A en B)
Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…
-
Selectieroutes (A en B)
Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…
-
A systematic literature review of security and privacy by design principles, norms, and strategies for digital technologies
Dit artikel biedt een systematisch literatuuronderzoek van de belangrijkste principes, normen en strategieën van Security by Design en Privacy by Design.
-
Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
-
Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: Prof.dr. J.N. Kok
-
Over ons
Wij bestuderen de dagelijkse praktijk van individuen, groepen en gemeenschappen - zowel in Nederland als wereldwijd - om ze te plaatsen binnen de complexe processen van sociale en globale ontwikkeling. In Leiden zijn we gespecialiseerd in de gevolgen van globalisering op het milieu, de sociale verhoudingen,…
-
Online Course Introduction to Comparative Indo-European Lingistics
Indo-European is the name of the language family to which English belongs, along with many sub-families such as Germanic languages and Romance languages. In this course, you will delve into the structure and origins of these branches, the oldest languages belonging to the language family, linguistic…
-
Psychology: a comprehensive introduction
Deze minor biedt een overzicht van het vakgebied Psychologie.
-
Euraziatische Rijken. Integratieprocessen en identiteitsvorming
What holds people together and what makes them willing to fit within larger political structures? Our project examines this question in the practices of dynastic rulership in Eurasia ca. 1300-1800.
-
Cavities for light and sound: a cavity-enhanced platform for quantum acoustics
Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).
-
networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
-
How to write a thesis
Dit boek neemt je stapsgewijs mee in het schrijven van een scriptie, met (voornamelijk) een focus op experimenteel onderzoek, dat het meest veel voorkomt. Door de stappen van experimenteel onderzoek in chronologische volgorde op te splitsen en bij elke stap tips te geven, hopen de auteurs enig houvast…
-
Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
-
Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
-
A song of ice and gas: the formation and evolution of complex organic molecules
Understanding how chemical complexity emerges during star formation requires connecting molecular material preserved in interstellar ices with that observed in the gas phase after protostellar heating begins.
-
Evolutionary adaptability of β-lactamase: a study of inhibitor susceptibility in various model systems
β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…
-
A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.
-
A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
-
Over Studeren à la carte
Bij Studeren à la carte of toehoorderschap is er sprake van aanschuifonderwijs: u schuift aan bij een reguliere collegereeks, zonder dat u tentamen aflegt. Na afloop ontvangt u een certificaat van deelname. Hierop staan geen studieresultaten (er is immers geen tentamen afgelegd).
-
The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
-
immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
-
resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the highest mortality rate, despite a relatively low incidence.
-
Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
-
I-Hsien LinFaculteit der Geesteswetenschappen
-
Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
-
A Model Membrane Approach to Elucidate the Molecular Organization in the Skin Barrier
Promotor: J. A. Bouwstra
-
Q&A Sessie Financieel Recht
Studievoorlichting, Q&A sessie
-
The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
-
What’s CLIL about bilingual education? A window on Content and Language Integrated Learning pedagogies
In Nederland bieden ongeveer 130 van de 700 middelbare scholen een tweetalige stroom aan. Toch is er nog maar weinig wetenschappelijk onderzoek naar CLIL (content and language integrated learning). Met haar proefschrift wil Evelyn van Kampen (promovendus bij het ICLON) bijdragen aan een beter begrip…
-
Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
-
Resolving a bioindicator diatom species complex using genomic approaches for freshwater biomonitoring
This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;
- Religion in a Changing World
-
A monodromy criterion for existence of Neron models and a result on semi-factoriality
In the first part, we introduce a new condition, called toric-additivity, on a family of abelian varieties degenerating to a semi-abelian scheme over a normal crossing divisor.
-
Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
-
They grow up so fast - Stellar accretion in a starburst cluster
When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.
-
Unraveling the surface formation of regular and deuterated water in space: a combined laboratory and computational study
Promotor: Prof.dr. H.V.J. Linnartz
-
The relation between dynamics and activity of phospholipase A/acyltransferase homologs
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.
-
From the root of variation: A metabolomics perspective to plant soil-feedback
By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.
-
Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
-
L.A.D. F. Kaiser
Het Leids Astronomisch Dispuut Frederik Kaiser is een vereniging die zich inzet voor de studenten die in Leiden sterrenkunde studeren. Daarnaast zijn ze ook erg betrokken bij de publieksactiviteiten in de Oude Sterrewacht en helpen ze bij de ontwikkeling en uitvoering van andere projecten in het geb…
-
A European Ministry of Finance?
Op 21 oktober 2021 verdedigde Frederik Behre het proefschrift 'A European Ministry of Finance?'. Het promotieonderzoek is begeleid door promotor prof.dr. S.C.G. Van den Bogaert.
-
Student for a day African Studies
Studievoorlichting
-
Student for a day African Studies
Studievoorlichting
-
Student for a Day - MSc Crisis and Security Management, spec. Governance of Crisis
Studievoorlichting
-
Student for a Day - MSc Crisis and Security Management, spec. Governance of Crisis
Studievoorlichting