A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Promotor: Prof.dr. G.J. Kroes

In de onderzoeksmaster Hebrew and Aramaic Studies (research) van de Universiteit Leiden is gericht op het bestuderen van de Hebreeuwse en Aramese taal en cultuur in de ruimste zin.

In this thesis I describe the results of Pulsed Interleaved Excitation and Fluorescence (Cross) Correlation Spectroscopy (PIE-F(C)CS) combined with single-pair Förster Resonance Energy Transfer (spFRET) used to study dynamics in single nucleosomes, which depends on subtle differences in the length of…

De Research Master Education and Child Studies is een Engelstalige master.

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Deze interdisciplinaire onderzoeksmaster biedt het beste van kunst, literatuur en media in een programma vol welontworpen vakken, waarin theoretische en historische vakken worden gecombineerd met vrije ruimte voor specialisatie.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

Deze opleiding is gericht op de ontwikkeling van computermodellen die de werking van medicijnen voorspellen, het individualiseren van bestaande behandeltherapieën en het ontwikkelen van innovatieve, analytische tools voor het personaliseren van de gezondheidszorg.

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

Curved single crystals provide variable, but well-defined surface structures.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Constraint multi-objective optimization with a limited budget for function evaluations is challenging. This thesis tackles this problem by proposing new optimization algorithms. These algorithms are applied on holistic ship design problems. This helps naval architects balance objectives like cost, efficiency,…

The elementary excitations of magnets are called spin waves, and their corresponding quasi-particles are known as magnons. The rapidly growing field of Magnonics aims at using them as information carriers in a new generation of electronic devices, (almost) free of electric currents.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Lipid nanoparticles (LNPs) have enabled the success of mRNA vaccines but remain limited in broader therapeutic use by challenges in delivery efficiency, targeting, and mechanistic understanding.

De onderzoeksgroep War, Peace and Justice onderzoekt de samenhang tussen oorlog, vrede en gerechtigheid. Met een multidisciplinaire aanpak brengen onderzoekers en praktijkdeskundigen nieuwe inzichten in conflict, duurzame vrede en mensenrechten, met bijzondere aandacht voor gender en veiligheid.

Promotor: E. Bouwman, Co-promotor: S. Bonnet

Het Platform for Arts Research in Collaboration (PARC) is een nieuw online en offline platform voor onderzoekers die werkzaam zijn op het gebied van compositie, muziek, kunst en design en daarbuiten, om kennis, ervaringen en openbare evenementen uit te wisselen, samenwerking te stimuleren en de zichtbaarheid…

Are you planning to conduct clinical research in the Netherlands? In this online course, you are introduced to legislation and procedures on clinical research in the Netherlands. It will help you prepare and submit your research file efficiently. The first three themes ‘The Dutch Review System’ , ‘The…

In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.

Op donderdag 16 november 2017 heeft Lalin Kovudhikulrungsri haar proefschrift ‘The Right to Travel by Air of Persons with Disabilities’ verdedigd. Haar promotoren zijn Prof.dr. P.M.J. Mendes De Leon en Prof.mr.dr. A.C. Hendriks.

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.

Promotor: Prof.dr. C.W.J. Beenakker

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.

Promotores: H.W. Lenstra, A. Lucchini

In de zaak Ferreira da Silva e Brito e.a./Estado portugues heeft het Hof van Justitie in het kader van overgang van onderneming expliciet de luchtvaartsector als kapitaalintensieve sector aangewezen. Hoe verhoudt het arrest zich tot het oordeel van het Gerechtshof Amsterdam over de overgang van de passagedivisie…

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

In this thesis, we address two problems concerning the tautological rings of the moduli space of curves.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Promotie

The University of Trento hosts the biennial conference of the International Reynard Society, taking place on September 25-28 2024. Deadline for paper/session submissions: December 31.

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

In deze master specialisatie ligt de focus op het begrijpen van biologische processen in hun natuurlijke context, zoals cellen en weefsels.