Deelproject van

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

In the first part of this thesis we study the geometry of folding patterns.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.

Lezing

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Gaucher disease is a rare metabolic disorder, in which a mutation of the enzyme glucocerebrosidase (GBA1) causes buildup of its substrate glucosylceramide and the deacylated counterpart glucosylsphingosine in lysosomes.

Preterm birth is a major contributor to neonatal morbidity and mortality and is associated with both acute complications and long-term health consequences.

Promotores: T.H. Oosterkamp, N. de Jonge

The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…

Neurolaw is een relatief jonge discipline, waarin de impact van de neurowetenschappen op het recht, de juridische praktijk en de criminologie wordt onderzocht. De actuele ontwikkelingen binnen de neurowetenschappen (neurobiologie, -psychologie en -psychiatrie) hebben de betekenis van onderzoek op dit…

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden

Kunst en vrije tijd, Kunst en vrije tijd

Studievoorlichting

Studievoorlichting

Op 8 juli 2020 verdedigde Andres Sarmiento Lamus zijn proefschrift 'The Proliferation of Dissenting Opinions in International Law'. Het promotieonderzoek is begeleid door promotoren prof.dr. L.J. van den Herik en prof.dr. Y.A.A.S. Radi (UCLouvain).

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Video games have emerged as one of the most interesting media of the turn of the century. The peculiar characteristic of video games is the biunivocal interaction between the computer and the human player.

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

Machine Learning is becoming a more and more substantial technology for industry.

Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

Promotores: J. Kok, M. Chaudron (Chalmers University)

In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.

De workshops zijn toegankelijk voor iedereen vanaf 17 jaar. Studenten van de Universiteit Leiden krijgen korting op de cursusprijs. Bekijk het gevarieerde aanbod hieronder. (de beeldende kunst workshops zijn inclusief gebruik materialen). Kies je workshop en schrijf je in!

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!

Catherina Wilson is op 1 oktober 2012 aan ons Instituut begonnen met een promotieonderzoek.

Read all about the experiences of our students who followed one of the Academic Language Center's (online) courses in the past semester.

Groeiende gezondheidsverschillen, toenemende zorgkosten, de vergrijzing en het tekort aan zorgpersoneel zijn slechts enkele voorbeelden van uitdagingen waar de gezondheidszorg voor staat, zowel in Nederland als daarbuiten. Deze vraagstukken overstijgen de grenzen van de medische sector en raken aan…

Van publieke organisaties wordt in toenemende mate verwacht dat zij maatwerk leveren en de menselijke maat meewegen in besluiten. De toeslagenaffaire, decentralisaties in het sociale domein en problemen bij uitvoeringsorganisaties hebben deze thema’s hoog op de politieke en bestuurlijke agenda gezet.…

In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…