1,221 zoekresultaten voor “chemistry weapons en ethics” in de Publieke website
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Kunstmatige fotosynthese
Voor de omzetting van zonlicht naar brandstof
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Functionalizing monolayer graphene as a proton-selective membrane for direct methanol fuel cells
This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.
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Synthesis and Characterization of Boron, Nitrogen, and Carbon-Based Two-Dimensional Materials
This thesis comprises the development of reproducible synthesis procedures for two-dimensional materials (composed of boron, nitrogen and carbon) on different metallic surfaces.
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From grains to planetesimals: the microphysics of dust coagulation
Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)
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Squaramide-based supramolecular materials for 3D cell culture applications
A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.
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The role and analysis of molecular systems in electrocatalysis
Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.
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The flux and flow of data: connecting large datasets with machine learning in a drug discovery envirionment
This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…
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Electroreduction of nitrate and carbon dioxide on copper electrodes: a mechanistic study
In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…
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Phase separation in lipid-based nanoparticles: exploring the nano-bio interface
This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.
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Squaramide-based supramolecular polymers : from self-assembly to in vivo application
The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.
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Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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Pyrrole-based photoswitchable anion receptors
The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.
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Applications of topology to Weyl semimetals and quantum computing
This thesis covers various applications of topology in condensed matter physics and quantum information.
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CO2 reduction on post-transition metals and their alloys: an industrial approach
This thesis focuses on the synthesis, characterization and performance towards CO2 electroreduction of mono and bi-metallic particles based on p-block metals
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Data structures for quantum circuit verification and how to compare them
Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.
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A fresh view on carbon radio recombination lines powered by LOFAR
The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Hydrogen dissociation on metal surfaces
Promotor: G. J. Kroes
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Squaramide-based interpenetrated networks for load-bearing applications
This thesis explores squaramide-based supramolecular polymers and hydrogels, enhancing their mechanical strength for 3D cell culture.
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Hermen Overkleeft wint de 2015 Jeremy Knowles Award
Prof. Hermen Overkleeft is bekroond met de 2015 Jeremy Knowles Award van de Royal Society of Chemistry voor zijn innovatieve en inzichtelijke ontwikkeling van activity-based eiwit probes voor de beeldvorming en de identificatie van enzymen in gezondheid en ziekte. Van Overkleeft is in Leiden verbonden…
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Willie PeijnenburgFaculteit der Wiskunde en Natuurwetenschappen
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Gamechangers
Onderzoek naar het ontwikkelen van privacy-vriendelijke zorg-games voor kinderen.
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The Hague Centre for Digital Governance
De opkomst van het digitale tijdperk beïnvloedt het openbaar bestuur op vele manieren. Digitalisering en data hebben invloed op elk aspect van openbaar bestuur en beleid. Binnen het instituut Bestuurskunde van de Universiteit Leiden, gevestigd in Den Haag - de bestuurlijke hoofdstad van Nederland -…
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Rechtsfilosofie
Rechtsfilosofie is in één woord samengevat de bezinning op de grondslagen van het recht.
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Maatschappelijk verantwoord ondernemen in de wereldwijde toeleveringsketen?
Mensenrechten zijn lang het unieke domein van staten geweest. Dat is veranderd met de globalisering en de opkomst van multinationale ondernemingen. De zorg voor fundamentele arbeidsrechten binnen mondiale toeleveringsketens vormt een probleem.
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Een kleine stap op platina, een grote stap voor de elektrochemie: Een realistischer beeld van platina-elektroden
De huidige elektrochemische theorie voldoet niet voor realistische platina-elektroden. Wetenschappers van de Universiteit Leiden hebben nu voor het eerst de invloed van imperfecte platina-oppervlakken in kaart gebracht. Dat geeft een beter beeld van deze elektroden, met toepassingen voor waterstofproductie…
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Obstinate Graves in East Java: Traditionalist and Modernist Ethics, Excess, and Sufi Perspectives | Research Seminar
Lezing, Research Seminar
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Lipasen: een nieuwe doelwit in de strijd tegen tuberculose
Hoe helpen lipasen in Mycobacterium tuberculosis de bacterie te overleven, en kunnen we deze enzymen gebruiken als doelwit voor nieuwe antibiotica?
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Oncode Accelerator
Nog altijd lukt het niet om alle kankerpatiënten van de juiste behandeling te voorzien. Oncode Accelerator wil daarom de manier waarop we kankerbehandelingen ontwikkelen innoveren: binnen het programma wordt de patiënt centraal gesteld. Universiteit Leiden en LUMC gaan hier samen met andere partijen…
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Communicatie over onzekerheden
Om goed onderbouwde besluiten over complexe onderwerpen zoals het klimaat, recht en gezondheid te kunnen nemen, zijn wetenschappelijke resultaten van groot belang. Maar wetenschappelijke resultaten bevatten altijd een mate van onzekerheid. Binnen het onderzoek Communicatie over onzekerheden wordt onderzocht…
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Onze mensen
Dit zijn de mensen die binnen de Universiteit Leiden actief zijn op het gebied van kunstmatige intelligentie.
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De geur van het universum
Voormalig promovendus Cameron Mackie krijgt niet één, maar twee proefschriftprijzen voor zijn proefschrift over het aromatische universum. Door zijn werk kunnen we binnenkort misschien een virtueel ‘snuifje’ van de ruimte nemen. ‘Deze moleculen in de ruimte ruiken waarschijnlijk als een grote houtsk…
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Connecting dots between natural and artificial Photosynthesis
Decentralized plug and play systems for energy production are the future picture of our society. Artificial photosynthetic systems are used for this purpose.
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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Studies of dust and gas in the interstellar medium of the Milky Way
Promotor: Prof.dr. A.G.G.M. Tielens
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The role of water in hydrogen electrocatalysis
Promotor: M.T.M. Koper, Co-promotor: L. Juurlink
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Water related adsorbates on stepped platinum surfaces
Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink
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Steps in gas-surface reactions
Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.
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Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
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X-ray spectroscopy of interstellar dust: from the laboratory to the Galaxy
In this thesis, we present new laboratory data of interstellar dust analogues.
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Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
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The optimization and scale-up of the electrochemical reduction of CO₂ to formate
Carbon dioxide capture and utilization technologies are necessary to create a truly circular economy. The electrochemical reduction of carbon dioxide to formate is an appealing carbon utilization method as it can be performed at room temperature and pressure, it only requires two electrons, and it has…