Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.

Sinds 2009 behaalden 91 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Studeren aan de Universiteit Leiden voor een paar uur per week? Een cursus, of een aantal vakken volgen? Er zijn diverse mogelijkheden voor geïnteresseerden om kennis op te doen bij eenvan de Leidse opleidingen.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

Op deze pagina vindt u de opnames van de online This Week's Discoveries vanaf 12 mei 2020 en een lijst sprekers vanaf oktober 2015.

Op deze pagina vind je de opnames van de Tuesday Talks sinds april 2025. Ook de opnames van de voorloper van de Tuesday Talks, This Week’s Discoveries, zijn hier te vinden

Op 12 januari 2022 verdedigde Mirjam Franke het proefschrift 'Over de grens van de onrechtmatige daad'. Het promotieonderzoek is begeleid door prof.mr. A.G. Castermans en prof.mr. J.H. Crijns.

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

CONSENT (Consumer sentiment regarding privacy on user generated content services in the digital economy) is a research project funded by the European Union under the 7th Framework Programme. The question central to this research is whether recent changes to consumer and commercial practices developed…

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Systems with local constraints is a new finding in recent researches on complex systems. The heterogeneous spatial interactions and the temporal dependencies among those numerous units make it difficult to describe by traditional statistical physics.

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.

The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Promotor: Prof.dr. H.A.G. Wijshoff

Welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit op het terrein van de rechten van de mens voor de effectieve bescherming van die rechten in een wereld die gekenmerkt wordt door pluralisme?

Workshop

How does one become a guest author for Nobel Prize winner Dr. Denis Mukwege Foundation? One of our alumni, Mariasole Forlani, can tell you all about it.

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

Studievoorlichting

Stress komt veel voor in de huidige samenleving. Dit is zorgwekkend, aangezien onderzoek herhaaldelijk heeft aangetoond dat stress een negatieve invloed heeft op de lichamelijke gezondheid. Zo vergroot stress bijvoorbeeld de kans op hart- en vaatziekten.

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

The ultimate aim of this project is to improve cooperation between courts in different Member States.

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski