2,857 zoekresultaten voor “research with animal” in de Publieke website
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Wild versus domestic prey in the diet of tigers
A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.
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Hoe klinkt de Waddenzee? Onderzoek brengt bruinvis en geluid in beeld
Waddenzeegeluiden: zo heet het project dat de Waddenvereniging samen met onderzoekers van Universiteit Leiden en Rijksuniversiteit Groningen start. Doel is te achterhalen wat de invloed van geluid op het onderwaterleven in de Waddenzee is.
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Jonathan BenichovFaculteit der Wiskunde en Natuurwetenschappen
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Research Achievement Award voor Meindert Danhof
Prof.dr. Meindert Danhof ontving op 15 november een Research Achievement Award in Pharmacokinetics, Pharmacodynamics & Drug Metabolism.
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Artikel in 'Psychological Research'
Het artikel ‘Putting emotions in routes: the influence of emotionally laden landmarks on spatial memory’ geschreven door Francesco Ruotolo, Michiel Claessen en Ineke van der Ham is verschenen in Psychological Research. Hierin wordt beschreven hoe de emotionele lading van de omgeving invloed heeft op…
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Digging for data: the rise and fall of a Miocene mammal biodiversity hotspot in the Vallès-Penedès (Catalonia, Spain)
The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.
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Convergent molecular evolution of toxins in the venom of advanced snakes (Colubroidea)
The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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The innate immune response against mycobacterial infection: analysis by a combination of light and electron microscopy
Promotores: Prof.dr. H.P. Spaink & Prof.dr. P.C.W. Hogendoorn Co-promotor: Dr. M.J.M. Schaaf
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Translational pharmacokinetics-pharmacodynamics in zebrafish: integration of experimental and computational methods
The zebrafish is a promising vertebrate model organism in early drug discovery and development.
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
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Lost in translation: The toll-like receptor 7 induced pharmacological challenge model of the skin
This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.
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Seeing voices: the role of multimodal cues in vocal learning
Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
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Marjolein Soethoudt wint Unilever Research Prijs 2013
Marjolein, Masterstudente Bio-Pharmaceutical Sciences, deed haar onderzoek op het raakvlak van de chemie en biologie naar zowel nieuwe medicijnen tegen diabetes als de mogelijke bijwerkingen ervan. Soethoudt ontdekte bovendien een manier om fouten bij medicijnontwikkeling in de toekomst te voorkomen.…
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A renewed awareness: Reinvigoratingpreparedness research for crisis and disastermanagement
IIn dit artikel blazen Jeroen Wolbers en Sanneke Kuipers het academische debat over rampenparaatheid nieuw leven in.
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EnSMiRT: European Network for Sustainable Mining Research and Transfer
EnSMiRT wil de expertise binnen de alliantie Una Europa benutten en de samenwerking tussen toonaangevende onderzoekers die in verschillende stadia van de minerale waardeketen werken, stimuleren om deze dringende uitdagingen rechtstreeks aan te pakken.
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Researching Extremists and Terrorists: Reflections on Interviewing Hard-to-Reach Populations
In deze publicatie verkennen Sarah Louise Carthy en Bart Schuurman de realiteit van het benaderen en interviewen van moeilijk bereikbare bevolkingsgroepen.
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Research Handbook on Public Affairs Connecting Evidence and Strategy
Arco Timmermans' handboek brengt experts samen om het vakgebied public affairs, de uitdagingen ervan en de relatie met democratie te verkennen.
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AI Literacy for Studying, Thesis Research, and Life
Lezing
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'Self-employment and satisfaction with life, work, and leisure'
Samen met mevrouw J. Hessels en de heer C.A. Rietveld heeft dr. P.W. van der Zwan het artikel 'Self-employment and satisfaction with life, work, and leisure' in de Journal of Economic Psychology gepubliceerd.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
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between television consumption and the attitudes toward people living with HIV/AIDS in Chile
We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…
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Afforesting with microbes: disentangling the effect of soil biotic and abiotic characteristics on trees using soil inoculation
In this thesis I examine how soil biotic and abiotic characteristics change and interact throughout the course of afforestation and how they subsequently impact tree performance.
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Why Minor Powers Risk Wars with Major Powers: A Comparative Study of the Post-Cold War Era
Aan de hand van een reeks case studies in Irak, Moldavië en Servië gedurende het post-Koude Oorlogstijdperk, onderzoekt dit boek asymmetrische conflicten waarbij de strijdende partijen een grote ongelijkheid in machtsposities vertonen.
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BRCA1-associated breast cancer: finding new weapons for an old villain
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Prof. dr. Joost Batenburg awarded with Vici grant 2015
The NWO (The Netherlands Organization for Scientific Research) awarded prof. Joost van Batenburg with the Vici grant 2015 for his research project ‘Real-time 3D Tomography’.
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Dance Improvisation: Soil Connections
Kunst en vrije tijd, Kunst en vrije tijd
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Peace Research Grant voor Femke Avtalyon-Bakker
In het kader van haar promotieonderzoek naar de invloed van de politieke cultuur van verschillende politieke regimes op individuen van deze samenlevingen heeft de Leidse politicoloog Femke Avtalyon-Bakker een beurs van de IPRAF (International Peace Research Organization Foundation) toegewezen gekreg…
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Exploring new methods at Research Lab Legal Data Science
How can data analytics be used as a research method in the field of legal research? This question was addressed during the Research Lab Legal Data Science on 23 September, 2016.
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The noisy underwater world: the effect of sound on behaviour of captive zebrafish
Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Dana Rademaker blinkt uit en wint Unilever Research Prize
Dana Rademaker heeft de Unilever Research Prize gewonnen. Ze ontving de prijs, samen met 2.500 euro, op 12 december bij het onlangs geopende Food Innovation Centre van Unilever. Ze behaalde afgelopen jaar haar Master Chemistry.
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Vacature: Research Assistant: Social Life of Medieval Canon Law
How does the medieval body of texts known as 'canon law' reflect social and moral ideas? With a combination of AI and an advanced dataset, can we reveal patterns in the transmission and alteration of these ideas over time? Join the SOLEMNE project as a research assistant to explore these questions and…
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Latest hardware for computer research on medical imaging
The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…
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One million euros for research on social security
Researchers from the Department of Economics - Kees Goudswaard, Koen Caminada, Marike Knoef, Pierre Koning and Olaf van Vliet - have been awarded a grant of one million euros by Instituut Gak to investigate self-sufficiency and social protection.
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Foundations of Research-2: Registration re-opened
Due to the COVID19 crisis (especially the impossibility to meet in person), the course "Foundations of Research-2" could not take place as scheduled. However, a second opportunity to participate in this course in October will be offered. The course is aimed at PhD students who are about halfway…
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Casimir Research School krijgt € 800.000 voor talentvolle promovendi
De Casimir Research School krijgt € 800.000 subsidie uit het NWO Graduate Programma om de masterstudie en het promotieonderzoek meer te integreren. Minister Plasterk vond het plan van het Leids-Delftse Casimir een van de beste.
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Research internships (Utrecht)
Research Internships of 15 ECTS are available in Medieval History at Utrecht University, from 2021-22 block 4 until 2023-24 block 3, for Research MA students.
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BRASILIAE. Indigenous Knowledge in the Making of Science: Historia Naturalis Brasiliae (1648).
Investigating the intercultural connections that shaped practices of knowledge production in colonial Dutch Brazil.
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Slotconferentie Facultair Research Traineeship
Hoe zag het kroegenlandschap van Leiden er in de negentiende eeuw uit? Waar komen specifieke gebaren in gebarentaal eigenlijk vandaan? Hoe werkten wetenschappers samen in onderzoeksprojecten voor het tijdperk van digitale communicatie?