1,991 zoekresultaten voor “that immune responses” in de Publieke website
-
Positive representations of algebras of continuous functions
If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.
-
Theory of mind in language, minds, and machines: a multidisciplinary approach
Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.
-
Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
-
Exploring the chemical space of natural products from Streptomyces using multi-omics approaches
The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.
-
Using commitment to improve environmental quality
Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats
-
Resolving gas-phase metallicity in galaxies
Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.
-
Counting metamaterials
The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.
-
Comparative genomics of the balanced lethal system in Triturus newts
All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?
-
Multiple star formation: chemistry, physics and coevality
Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.
-
Split Jacobians and Lower Bounds on Heights
This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.
-
Uncovering the ingredients for planet formation
This thesis discusses the physical and chemical processes than influence the composition of forming planets.
-
Interactions from lipid membrane deformations
Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.
-
Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
-
Financial Collateral
In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…
-
Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
-
The rebound effect through industrial ecology’s eyes : the case of transport eco-innovation
Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)
-
Phenotypic plasticity and genetic adaptation of plant functional traits on global scales
In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…
-
Optimally weighted ensembles of surrogate models for sequential parameter optimization
It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.
-
Onderzoek
Onderzoek van de sectie Methodologie & Statistiek van het Instituut Psychologie aan de Universiteit Leiden
-
When materials become critical: lessons from the 2010 rare earth crisis
Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn
-
Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
-
Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
-
Towards near-infrared light-activated combination chemotherapy
The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.
-
Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
-
Climate Call
In 2019 startte LUGO een petitie met het verzoek om een ambitieuze duurzaamheidsvisie voor 2030. Deze petitie is geformuleerd op basis van wat LUGO haalbaar achtte in plaats van op de beperkingen van nu. Wij vinden dat duurzaamheid een van de kernwaarden moet zijn van het volgende centrale beleidsplan…
-
Acquired resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the highest mortality rate, despite a relatively low incidence.
-
Colloidal mechanical metamaterials
This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.
-
Blueprints of Disease: Precision Platforms for Modelling Breast Cancer
Breast cancer (BC) is a clinically and biologically heterogeneous disease.
-
Kiki SpaninksFaculteit der Wiskunde en Natuurwetenschappen
-
Matching, entropy, holes and expansions
In this dissertation, matching, entropy, holes and expansions come together. The first chapter is an introduction to ergodic theory and dynamical systems.
-
On hard real-time scheduling of cyclo-static dataflow and its application in system-level design
Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov
-
A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
-
Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
-
Underground alarms: volatile-mediated recruitment of beneficial soil bacteria by plants under biotic stress
Beneficial plant-associated microbiota, particularly those inhabiting the rhizosphere, contribute substantially to plant health through pathogen suppression, stimulation of plant defence responses, and enhanced nutrient acquisition.
-
Capturing dynamics with noisy quantum computers
Quantum computing represents a fundamentally new computational paradigm, capable of addressing problems that are intractable for classical computers.
-
Mathematical models for mechanically induced morphogenetic pattern formation
During the development of the (human) body from a single fertilized egg, organs and structures must form. The development and growth of biological forms is called morphogenesis.
-
Threading the needle: constraining the stellar content and dynamics of the Galactic Centre with hypervelocity stars
In this thesis we use state-of-the-art observations and simulations to provide the best constraints to date on the HVS ejection rate and constraints on the stellar content and dynamics at the GC, including the progenitor binary populations and their star formation history.
-
Rebekah Tromblé
Students Practicing Citizen Journalism
-
Internships
There are study programmes at LIACS that offer the opportunity to do an internship or research project, as part of the curriculum.
-
Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
-
Applications of graphene in nanotechnology : 1D diffusion, current drag and nanoelectrodes
Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).
-
Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
-
A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
-
Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
-
Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
-
Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
-
Enumeration and Simulation of Lattice Polymers as Models for Compact Biological Macromolecules
Promotores: H. Schiessel, G.T. Barkema
-
Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
-
Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
-
RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.