2,923 zoekresultaten voor “research with animal” in de Publieke website
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Metabolomics study of blood vessels-on-chip model
Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.
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Orchid mycorrhizal interactions: evolutionary trajectories and ecological variations
The mycorrhizal symbiosis is among the most widespread species interactions on Earth. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries.
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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North Sea noise in the Anthropocene: an impact study of human-made impulsive sounds on free-ranging cod
Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.
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Modulating the behaviour of pancreatic tumour cells
Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink. Co-promotor: C.P. Bagowski
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
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Chemiestudent Hans de Bruijn wint promotieplaats Holland Research School
Hans de Bruijn studeerde cum laude af en schreef zijn onderzoeksplan tijdens een speciale masteropleiding voor getalenteerde chemiestudenten van de Holland Research School (HRSMC). Zijn voorstel werd gehonoreerd en De Bruijn start later dit jaar zijn door NWO en HRSCM gefinancierde promotietraject.
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A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.
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Human Frontier Science Program prijs voor Katharina Riebel
Een internationaal onderzoeksteam metgedragsbioloog Katharina Riebel als hoofdonderzoeker en twee internationale medewerkers ontving een Human Frontier Science Program (HFSP) beurs voor het hun onderzoeksvoorstel ‘Seeing voices’: the role of multimodal cues in vocal learning.
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Eliza Steinbock: ‘Mijn research is eigenlijk een soort me-search’
Ik ben Eliza Steinbock, 38 jaar en geboren en getogen in Louisville, Kentucky in de Verenigde Staten. Vanaf 2014 werk ik aan de Universiteit Leiden waar ik lesgeef en onderzoek doe naar genderrepresentatie, met name de representatie van transseksuele mensen, in cultuur en media.
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Wetenschappelijke publicaties
Een lijst met wetenschappelijke publicaties samengesteld door het team van het TRIXY Expertisecentrum.
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Comorbidities, complications and treatment of childhood obesity
Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.
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Acquired resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the highest mortality rate, despite a relatively low incidence.
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Carsten de Dreu is benoemd als Distinguished Research Fellow in Oxford
De Leidse sociaal psycholoog Carsten de Dreu is door zijn benoeming als Distinguished Research Fellow verbonden aan de University of Oxford om mee te denken en te werken aan een groot onderzoek naar besmettelijke ziekte.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Petrus Camper’s Research on Elephants: Cabinets, Menageries, and the Zoology of Exotic Animals in the Eighteenth-Century Dutch
Lezing, COGLOSS Seminar
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Nieuwe serie research seminars over onderzoek bij de Faculteit Governance and Global Affairs
De Faculteit Governance and Global Affairs introduceert met genoegen een nieuwe serie research seminars. Het FGGA Research Seminar zal een forum zijn voor de presentatie van en discussie over actueel hooggekwalificeerd onderzoek naar onderwerpen waar de faculteit zich mee bezig houdt.
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Publicatie: Artistic Research in Music: Discipline and Resistance - Artists and Researchers at the Orpheus Institute
Publicatie boek 'Artistic Research in Music: Discipline and Resistance' markeert 20-jarig jubileum Orpheus Instituut.
- Boulder session with YAL & JUL
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Derde jaarlijkse ‘Law and Development Research Network’-conferentie 19 t/m 21 september 2018
Van 19 t/m 21 september werd de derde jaarlijkse ‘Law and Development Research Network’-conferentie gehouden in het Museum Volkenkunde in Leiden.
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Photocleavable activity-based acid glucosylceramidase probes
Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…
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Perovskite-based Photoelectrochemical Investigations for Artificial Photosynthesis
Inspired by natural photosynthesis, perovskite-based photoelectrochemical (PEC) systems are being developed for artificial photosynthesis, aiming to enhance solar-to-hydrogen conversion for green energy.
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Studenten sluiten research traineeship af: ‘Goede start voor een carrière als onderzoeker’
Na zeven maanden hard werken was het zover: de deelnemers aan het Research Traineeship Programme sloten vrijdag 2 september hun onderzoek af met een pitch en een posterpresentatie.
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Jannemieke Ouwerkerk ontvangt Humboldt Research Fellowship
De Duitse Alexander von Humvoldt Stiftung heeft aan Jannemieke Ouwerkerk een Humboldt-Forschungsstipendium für erfahrene Wissenshaftler toegekend voor haar project The Moral Limits of EU Criminal Law: A Rechtsguts-theory for the European Union.
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Bacteriën die plastic afbreken: Unilever Research Prize voor masterstudent Jo-Anne Verschoor
Jo-Anne Verschoor is winnaar van de Unilever Research Prize 2020. De masterstudente Biologie ontwikkelde een methode om te testen of bacteriën in staat zijn om plastic af te breken. Verschoor: ‘Met behulp van specifieke enzymen uit deze bacteriën kunnen we in de toekomst wellicht efficiënt plastic r…
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Studenten adviseren veiligheidsexperts: ‘Fantastische combinatie van research en praktijk’
Een weldoordacht idee presenteren aan Schiphol-deskundigen, een oud-ambassadeur of een veiligheidsexpert. Voor studenten van de bachelor Security Studies was dit vorige week een unieke ervaring én een grote kans. ‘Wie weet kunnen ze in de toekomst bij ons aan de slag!’
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Saqqara Excavations and Fieldschool (Egypt)
Our recent excavations have focused on the more recent New Kingdom/Late Period (ca. 1500-332 BCE) material.
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Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
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Cavities for light and sound: a cavity-enhanced platform for quantum acoustics
Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).
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Opinion Dynamics on Random Graphs
This thesis investigates opinion dynamics on random graphs through the lens of the voter model, a classical interacting particle system used to describe how consensus emerges in networks.
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Focal-plane wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
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Effects of slug herbivory on seedling recruitment in Brassica napus and B. rapa
Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong
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Algebraic filters for filtered backprojection
Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit
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Revealing the nature of new low-frequency radio source populations
It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.
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Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
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Atmospheres of hot alien Worlds
Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Metabolomic characteristics of Catharanthus roseus plants in time and space
Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Nieuw Research Support Portal: alle informatie over onderzoeksondersteuning op één plek
Alle informatie over de beschikbare onderzoeksondersteuning aanbieden op één plaats, dat is de bedoeling van het nieuwe Research Support Portal. Beleidsmedewerker onderzoek Marcel Belderbos vertelt over het onlangs gelanceerde platform.
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Conservation and management of lions in Kenya
Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.
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Connect & Disclose the use of generative AI with the FAIR AI Attribution (FAIA) framework
Webinar with Q&A
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Graduation MIRD Class of 2024: 'The world is better off with students like this'
Graduation MIRD Class of 2024: 'The world is better off with students like this'
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New IB student member Pablo wants to engage students more closely with the institute
Per 1 september volgt Pablo Pandocchi Thirza van 't Rood op als student-lid van het Instituutsbestuur het komend academisch jaar. Het IB is verantwoordelijk voor alle zaken die het instituut aangaan, van onderwijs tot onderzoek op het gebied van antropologie en sociologie. Tweedejaars student CADS Pablo…
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Dr. Charlene Kalle and Dr. Tim van Erven awarded with TOP-grant
Dr. Charlene Kalle and dr. Tim van Erven, both assistant professors at the Mathematical Institute of Leiden University have received a TOP grant for Physical Sciences from the NWO (The Netherlands Organization for Scientific Research).
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Partnering Heritage with Latin America: Heritage Futures in the Age of Polycrises
Explore how cultural heritage can proactively respond to global crises, from geopolitical conflicts to climate change, through innovative cross-cultural collaboration between Latin American stakeholders and Una Europa.
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Topological aspects of rational points on K3 surfaces
Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk
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Communicating in Legal English
Ontdek de cursus Communicating in Legal English van de Leiden Law Academy en verbeter uw juridisch Engelse vaardigheden. Lees hier meer!